Video Of the Year
- Beyonce - Irreplaceable
- Justice - D.A.N.C.E.
- Rihanna featuring Jay-Z - Umbrella
- Justin Timberlake - What Goes Around...Comes Around
- Kanye West - Stronger
- Amy Winehouse - Rehab
Male Artist of the Year
- Akon
- Robin Thicke
- T.I.
- Justin Timberlake
- Kanye West
Female Artist of the Year
- Beyonce
- Fergie
- Nelly Furtado
- Rihanna
- Amy Winehouse
Best Group
- Fall Out Boy
- Gym Class Heroes
- Linkin Park
- Maroon 5
- White Stripes
Best New Artist
- Lily Allen
- Gym Class Heroes
- Peter Bjorn and John
- Carrie Underwood
- Amy Winehouse
Most Earthshattering Collaboration
- Akon featuring Eminem - Smack That
- Beyonce and Shakira - Beautiful Liar
- Gwen Stefani featuring Akon - The Sweet Escape
- Justin Timberlake featuring Timbaland - SexyBack
- U2 featuring Green Day - The Saints are Coming
Quadruple Threat of the Year
- Beyonce
- Bono
- Jay-Z
- Justin Timberlake
- Kanye West
Monster Single of the Year
- Daughtry - Home
- Fall Out Boy - Thnks fr th Mmrs
- Avril Lavigne - Girlfriend
- Lil Mama - Lip Gloss
- MIMS - This Is Why I'm Hot
- Plain White T's - Hey There Delilah
- Rihanna featuring Jay-Z - Umbrella
- Shop Boyz - Party Like a Rockstar
- T-Pain featuring Yung Joc - Buy You a Drank (Shawty Snappin')
- Timbaland featuring Keri Hilson - The Way I Are
More nominations...
