50. Kelis - "Acapella"
Courtesy A&M
Kelis returned in 2010 and moved away from strong R&B to a more electronic dance oriented sound. The inspirational lyrics are inspired by her son Knight.
49. OneRepublic - "Secrets"
Courtesy Interscope
If you feel that you tend to run into the song "Secrets" nearly everywhere, it's probably not your imagination. OneRepublic's hit has been featured in a wide range of TV shows as well as advertising by Ralph Lauren and for Apple's iPhone 4. It is a grand, sweeping ballad in the tradition of the group's first major hit "Apologize."
48. Matisyahu - "One Day"
Courtesy Epic Records
Matisyahu's spiritually uplifting prayer for peace in our world was used extensively as a theme song for NBC's coverage of the 2010 Winter Olympics.
47. Young Money featuring Lloyd - "Bedrock"
Courtesy Cash Money Records
The Cash Money hip hop label rolled out its superstar list of young rap artists to put together this clever collaborative effort. Nicki Minaj, Drake, and Lloyd are among those featured here.
46. Travie McCoy featuring Bruno Mars - "Billionaire"
Courtesy Fueled By Ramen
Travie McCoy stepped away from his group Gym Class Heroes for this first solo effort. Honey sweet vocals on the hook by Bruno Mars helped it become a top 5 smash.
45. Justin Bieber featuring Ludacris - "Baby"
Courtesy Island Records
This lead single from Justin Bieber's second album My World 2.0 gets a lot of the credit for making him truly a world pop superstar. "Baby" rolled into the top 5 in the US, UK, Canada and Australia. It proved he can deliver a hit single that instantly sounds timeless in its appeal.
44. Sara Bareilles - "King Of Anything"
Courtesy Epic
The lead single from Sara Bareilles' album Kaleidoscope Heart delivers more of the literate piano-based pop that animated her breakthrough "Love Song." It was inspired by her frustration with the amount of unsolicited advice she has received from others on how to live her life.
43. Chris Brown - "Yeah 3X"
Courtesy Jive
Chris Brown continued the rehabilitation of his mainstream pop career by heading back to the type of R&B dance music that made him a pop star in the first place. Watch the music video to enjoy Chris Brown's immense dancing talent as well.
42. La Roux - "Bulletproof"
Courtesy Polydor
80s dance pop is the touchstone for this US debut hit by the duo La Roux. Ultimately "Bulletproof" amounts to a bit of an "I Will Survive" for a new generation.
41. Edward Maya and Vika Jigulina - "Stereo Love"
Courtesy Ultra
Romanian musician and producer Edward Maya created an international pop sensation with this adaptation of an Azerbaijani song. The record reached #1 in at least 10 different countries before making it to the US.
